vivoPharm offers the following range of mammalian toxicology services:

  • Acute toxicity studies:
    • Single and repeat dose studies up to 14-days duration according to OECD Test Guidelines or custom study design
    • Custom design for dose range finding and maximum tolerated dose studies
    • Dermal toxicity
    • Skin irritation/corrosion test in rabbits
    • Local lymph node skin sensitisation test in mice
  • 28-day and 13-week repeat dose toxicity studies
    • Repeat dose studies according to OECD Test Guidelines
  • Chronic toxicity studies
    • 6-, 9- or 12-month duration
  • Toxicokinetic studies
  • Skin sensitisation and skin irritation studies
  • Supporting services
    • Clinical pathology including in-house haematology, clinical biochemistry, histopathology analyses
    • Bioanalytical support for toxicokinetic studies
    • Consulting Services

Administration routes available include:

  • Oral
  • Subcutaneous
  • Intravenous injection
  • Intraperitoneal
  • Percutaneous
  • Dermal
  • Vaginal
  • Rectal
  • Urinary Bladder

The above studies can be performed in a range of species. vivoPharm has exceptional expertise in rodent toxicology studies. Guinea pig and rabbit studies are also performed in-house. Dog and non-human primate studies are performed with vivoPharm’s GLP compliant partners.

Services are performed in compliance with regulatory authority test guidelines and are fully GLP compliant.

Non-GLP services are also available on request.

vivoPharm HQ • Level 3 Office 29 • 240 Plenty Road • Bundoora VIC 3083 Australia

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